Home Pharmacy Care Services in Improving Medication Adherence in Diabetic and Hypertensive Patients: A Systematic Review on Ethics and Regulatory
DOI:
https://doi.org/10.54445/pharmademica.v5i1.97
Abstract View:
74
PDF downloads:
43
Keywords:
adherence, diabetes, ethics, home pharmacy care, hypertension, regulationAbstract
Home pharmacy care is a part of community pharmacy service that is critical in improving patient adherence, which is a significant challenge in managing chronic diseases. One approach that can help overcome this problem is the practice of home pharmacy care. The current study aimed to evaluate the role of home pharmacy care interventions can enhance medication adherence among diabetic and hypertensive patients and to examine the ethical and regulatory aspects associated with its implementation. A systematic review was conducted based on the PRISMA guidelines, using the keywords “home pharmacy care” AND (diabetes mellitus OR hypertension) AND kepatuhan, home pharmacy care AND diabetes mellitus AND (adherence OR compliance), home pharmacy care AND hypertension AND (adherence OR compliance) on Google Scholar and PubMed databases with a search time limit from January 2015 to May 2025. The ethical and regulatory analysis was conducted by reviewing secondary literature regulating home pharmacy care and professional codes of ethics. Out of a total of 290 identified articles, only 10 met the inclusion criteria for further analysis. Based on the ten reviewed articles, it was stated that home pharmacy care interventions can enhance medication adherence among patients with diabetes mellitus and hypertension. However, the implementation of this service faces challenges, such as ethical concerns and regulatory limitations. The development of comprehensive regulations and consistent application of the code of ethics are expected to strengthen legal protection for pharmacists and improve the quality of home pharmacy care services.
Downloads
References
Ardiyansyah. (2020). Perlindungan Hukum terhadap Apoteker yang Melakukan Home Pharmacy Care dalam Hal Keadaan Kedaruratan. Indonesian Private Law Review, 1(1), 55–64. https://doi.org/10.25041/iplr.v1i1.2048
Depkes RI. (2008). Pedoman Pelayanan Kefarmasian di Rumah (Home Pharmacy Care). Jakarta: Departemen Kesehatan Republik Indonesia.
Hati, A. K., Karminingtyas, S. R., Devi, D. A., & Wati, B. R. D. (2019). Evaluasi Kepatuhan Minum Obat Pasien Diabetes Melitus Tipe 2 di Fasilitas Kesehatan Tingkat Pertama UPTD Puskesmas Ungaran dan UPTD Puskesmas Ambarawa dengan Intervensi Pemberian Home Pharmacy Care. Indonesian Journal of Pharmacy and Natural Product, 2(1), 11–18. https://doi.org/10.35473/ijpnp.v2i1.191
IAI. (2022). Surat Keputusan Kongres ke-XXI Ikatan Apoteker Indonesia Nomor: 014/KONGRES.IAI/XXI/VI/2022 tentang Penetapan Kode Etik Apoteker Indonesia Tahun 2022. Bandar Lampung: Ikatan Apoteker Indonesia.
IDF. (2025). IDF Diabetes Atlas (11th ed.). Brussels: International Diabetes Federation.
Illahi, R. K., Hariadini, A. L., Pramestutie, H. R., & Diana, H. (2019). Efektivitas Home Pharmacy Care dalam Meningkatkan Pengetahuan dan Kepatuhan terhadap Pengobatan Pasien Hipertensi (Studi Dilakukan selama 3 Bulan di Apotek Kota Malang). Pharmaceutical Journal of Indonesia, 5(1), 21–28.
Katadi, S., Andayani, T. M., & Endarti, D. (2019). Hubungan Kepatuhan Pengobatan dengan Outcome Klinik dan Kualitas Hidup Pasien Diabetes Melitus Tipe 2. Jurnal Manajemen Dan Pelayanan Farmasi, 9(1), 19–26. https://doi.org/10.22146/jmpf.42927
Kemenkes RI. (2016). Peraturan Menteri Kesehatan Republik Indonesia Nomor 73 Tahun 2016 tentang Standar Pelayanan Kefarmasian di Apotek. Jakarta: Kementerian Kesehatan Republik Indonesia .
Kemenkes RI. (2023a). Keputusan Menteri Kesehatan Republik Indonesia Nomor HK.01.07/Menkes/2015/2023 tentang Petunjuk Teknis Integrasi Pelayanan Kesehatan Primer. Jakarta: Kementerian Kesehatan Republik Indonesia.
Kemenkes RI. (2023b). Survei Kesehatan Indonesia (SKI) 2023 dalam Angka. Jakarta: Kementerian Kesehatan Republik Indonesia.
Larasanty, L. P. F., Meilinayanti, N. M. L., Susanti, N. M. P., & Wirasuta, I. M. A. G. (2015). Pengaruh Pelayanan Kefarmasian Residensial terhadap Ketaatan dan Luaran Klinis Pasien Hipertensi. Jurnal Farmasi Klinik Indonesia, 4(3), 162–174. https://doi.org/10.15416/ijcp.2015.4.3.162
Najiha, M. R., Utaminingrum, W., & Wibowo, M. I. N. A. (2017). Peran Home Pharmacy Care pada Pasien Diabetes Mellitus Tipe II Prolanis terhadap Tingkat Kepatuhan dan Keberhasilan Terapi di BP Sentra Medika Lebaksiu Tegal. Journal of Tropical Pharmacy and Chemistry, 4(2), 60–65. https://doi.org/10.25026/jtpc.v4i2.134
Padmasari, S., Azizah, F. N., & Larasati, N. (2021). Edukasi Home Pharmacy Care terhadap Kepatuhan dan Kontrol Glukosa Darah pada Pasien Diabetes Melitus. Jurnal Sains Farmasi & Klinis, 8(2), 182–189. https://doi.org/10.25077/jsfk.8.2.182-189.2021
Pemerintah RI. (2023). Undang-undang Nomor 17 Tahun 2023 tentang Kesehatan. Jakarta: Pemerintah Republik Indonesia.
Pemerintah RI. (2024). Peraturan Pemerintah Nomor 28 Tahun 2024 tentang Peraturan Pelaksanaan Undang-Undang Nomor 17 Tahun 2023 tentang Kesehatan. Jakarta: Pemerintah Republik Indonesia.
Rahmawati, I. R., & Yulianti, D. (2024). Evaluasi Kepatuhan Terapi Obat pada Pasien Diabetes Melitus di Rawat Jalan RSUP Fatmawati. Jurnal Farmasi Klinik Best Practice, 3(1), 10–18. https://doi.org/10.58815/jfklin.v3i1.39
Ravindra, B. N., & Kaushik, A. (2022). Effect of Pharmacy Home Medications Review Services on Drug-Related Issues among the Elderly Population. International Journal of Advance and Applied Research, 10(1), 1306–1315.
Rikmasari, Y., Munarsih, E., & Alfionita, H. (2024). Adherence and Clinical Outcomes of Hypertensive Patients in Rural Areas after Receiving Home Pharmacy Care Interventions. Jurnal Penelitian Sains, 26(1), 117–123. https://doi.org/10.56064/jps.v26i1.947
Rokhman, M. R., Darakay, C. N., & Raditya, R. (2015). Pengaruh Pemberian Home Care oleh Apoteker pada Pasien Diabetes Melitus. Jurnal Manajemen Dan Pelayanan Farmasi, 5(3), 225–232.
Rosli, M. R., Neoh, C. F., Wu, D. B., Hassan, N. W., Mahmud, M., Rahimi, A., & Karuppannan, M. (2021). Evaluation of Home Medication Review for Patients with Type 2 Diabetes Mellitus by Community Pharmacists: A Randomised Controlled Trial. Pharmacy Practice, 19(3), 2397. https://doi.org/10.18549/PharmPract.2021.3.2397
Sari, Y. O., Permatasari, D., Mariza, W., Fitria, N., & Lailiani, R. (2022). Application of Home Medication Review (HMR) on Patient Adherence in Type 2 Diabetes Mellitus (T2DM) Blood Sugar Management. Jurnal Sains Farmasi & Klinis, 9(sup), 160–167. https://doi.org/10.25077/jsfk.9.sup.160-167.2022
Sholichin, Layun, M. K., & Syahrun. (2021). Gambaran Tingkat Kepatuhan Pasien dalam Minum Obat Anti Hipertensi. Indonesian Journal of Health Research, 4(2), 52–58.
Utaminingrum, W., Pranitasari, R., & Kusuma, A. M. (2017). Pengaruh Home Care Apoteker terhadap Kepatuhan Pasien Hipertensi. Jurnal Farmasi Klinik Indonesia, 6(4), 240–246. https://doi.org/10.15416/ijcp.2017.6.4.240
WHO. (2023). Hypertension. Retrieved from https://www.who.int/news-room/fact-sheets/detail/hypertension
Widyastuti, S., Yasin, N. M., & Kristina, S. A. (2019). Pengaruh Home Pharmacy Care terhadap Pengetahuan, Kepatuhan, Outcome Klinik dan Kualitas Hidup Pasien Hipertensi. Majalah Farmaseutik, 15(2), 105–112. https://doi.org/10.22146/farmaseutik.v15i2.47623
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Ida Ayu Alit Widhiartini, I Komang Aan Adi Ricardo, Ni Putu Wika Pebrianti, Putu Yudha Kartika Pratama
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
.png)
