PHARMADEMICA : Jurnal Kefarmasian dan Gizi <p><strong>PHARMADEMICA : Jurnal Kefarmasian dan Gizi</strong> is an Open Access Scientific Journal published by LPPM-KI Politeknik Kesehatan Putra Indonesia Malang (POLTEKKES PIM, formerly AKAFARMA-AKFAR PIM). <strong>PHARMADEMICA : Jurnal Kefarmasian dan Gizi</strong> publishes original research article in all areas of :</p> <ol> <li>Clinical Pharmacy</li> <li>Pharmaceutical Chemistry</li> <li>Pharmaceutics</li> <li>Community Pharmacy</li> <li>Pharmacognosy</li> <li>Phytochemistry</li> <li>Pharmaceutical Analysis</li> <li>Biochemistry</li> <li>Clinical Nutrition</li> <li>Community Nutrition</li> <li>Functional Foods</li> </ol> <p><strong>PHARMADEMICA : Jurnal Kefarmasian dan Gizi</strong> accepts submissions all year round. Editorial board receives the articles from the educators, observers, researchers to be published after having selection, peer review, and serious editing. This journal publishes a manuscript written in Indonesian, twice a year in March and September.</p> en-US [email protected] (apt. Dr. Bilal Subchan Agus S. M.Farm.) [email protected] (Farid) Mon, 29 Apr 2024 00:00:00 +0700 OJS 60 Identification of Flavonoid Compounds in Several Types of Plants Using Thin Layer Chromatography: Literature Review <p><em>Flavonoids</em><em> are one of the secondary metabolites contained in plants, and can be used as anti-microbial, wound infection medicine, anti-fungal, anti-viral, anti-cancer and anti-tumor. This research reviews the isolation and identification of flavonoid secondary metabolite compounds from various parts of plants using the thin layer chromatography (TLC) method with the retention factor (Rf) value parameter. Data from various previous research articles are presented in tables, showing variations in Rf values obtained from the use of different eluents. The results showed that the eluent used influenced the Rf value, with ethanol eluent tending to provide high Rf values (above 0.9), indicating higher validity in flavonoid identification. This implication is important for understanding and interpreting the results of flavonoid analysis in plant research.</em></p> Anisa Oktaviana Putri, Mentari Cahaya Hati, Nasywa Putri Ishanti, Hilda Srivaliana Ilham Copyright (c) 2024 Anisa Oktaviana Putri, Mentari Cahaya Hati, Nasywa Putri Ishanti, Hilda Srivaliana Ilham Mon, 29 Apr 2024 00:00:00 +0700 Physical Quality and Chemical Quality of Solid Soap with Various Concentrations of Turmeric Extract (Curcuma domestica) <p><em>Turmeric</em> <em>(Curcuma domestica) contains curcumin which can provide antioxidant and antibacterial activity. Curcumin can also be used as a natural brownish yellow dye at alkaline pH, so it can be used as an additional ingredient in making solid soap. This research aims to determine the physical quality a chemical quality of solid soap preparations with varying concentrations of turmeric extract. This research includes descriptive research which includes making turmeric extract, making solid soap with varying concentrations of turmeric extract concentration of 2 gram (F1), 3 gram (F2) and 4 grams (F3) as well as physical quality testing which includes organoleptic, water content, foam stability and chemical quality testing include pH, fee alkali and free fatty acids. The results of the physical quality test of the 3 soaps formulation were brown soap, solid and odourless. Water content for F1: 0,6486%, F2: 0,4897%, F3: 0,5228%. Foam stability for F1: 5,5 cm, F2: 5,3 cm, F3: 5,3 cm. The chemical quality test result for pH are F1: 8,54, F2: 8,81, F3: 8,94 while free alkali for F1: 0,0428%, </em>F2:<em> 0,0429% dan F3: 0,0461%. Based on the research that has been carried out, it can be conclude that the three solid soap formulas with v</em><em>a</em><em>rying concentrations of turmeric extract have content, foam stability, pH and free alkali in accordance with SNI-3532-2016</em><em>.</em></p> wahyu wuryandari, Andreas Candra Firnanda Copyright (c) 2024 wahyu wuryandari, Andreas Candra Firnanda Mon, 29 Apr 2024 00:00:00 +0700 Formulation and Evaluation of Belt Leaf Extract Cream Preparation with Varied Concentrations Of 96% Ethanol as Anti-Septic <p><em>The</em> <em>b</em><em>e</em><em>t</em><em>e</em><em>l leaf plant (Piperis betle Linn) is a plant that is very easy to find in the surrounding environment. One of the benefits of the betel leaf plant is for treatment as an antiseptic because it contains flavonoid compounds. In order to make it easier for users to use betel leaves (Piperis betle Linn) as an antiseptic, the leaves are extracted with 96% ethanol and then formulated in cream form. This research aims to determine the results of concentration variations on the antiseptic activity of 96% ethanol extract cream from betel leaves on wound healing. Betel leaves (Piperis betle Linn) were extracted using the maceration method using</em> <em>96% ethanol. Then the extract is made into a cream mass with varying concentrations of the active substance of 4%, 8% and 12%. The results of research on the formulation and evaluation of betel leaf extract cream</em> <em>can be concluded that betel leaves can be formulated as an antiseptic. The results of the physical evaluation</em> <em>show that the betel leaf extract cream has the best preparation in formula II with a concentration of 4%</em> <em>because the cream is included in the test range</em>).</p> Hilfa Qurrotul Aini, Pemta Tiadeka, Janatun Naimah Copyright (c) 2024 Hilfa Qurrotul Aini, Pemta Tiadeka, Janatun Naimah Mon, 29 Apr 2024 00:00:00 +0700 Potential of Suweg Tumber Flour Cereal (Amorphophallus companulatus) as Weight Reducing in Male Mice with A High Fat Diet <p><em>Suweg</em><em> tubers (Amorphophallus companulatus) is a plant that grows wild and is widely used as fodder. The largest component in suweg tuber is carbohydrate that is 80%-85% with glukomanan. Glukomaman is a natural polysaccharide which cannot be hydrolyzed by digestive enzymes in the human body and is known as a no-calorie compounds. This study aims to determine the effect of cereal-based flour suweg tubers (Amorphophallus companulatus) against weight loss of male mice with high fat diet. Process to made flour from suweg tuber, was cleaned and chopped. Chopped then soaked with salt water then dried and powdered. The yield in flour were obtained by 5.2%. Suweg tubers flour that has been processed into cereal. Cereals made with three variations of the formula that is with the addition of </em><em>75g:25g</em><em>, 50</em><em>g:g50 and 75g:25g in each recipe. The result cereal flake shaped, sweet flavor, color suweg flour browned and flavorful, and the formula 1 with the addition is a formula which gives the effect of the most in reducing weight.</em></p> Ayuk Marta, Fitri Eka Lestari, Dwi Handayani, Gita Ardelia Copyright (c) 2024 Ayuk Marta, Fitri Eka Lestari, Dwi Handayani, Gita Ardelia Mon, 06 May 2024 00:00:00 +0700 The Influence of Different Plant Extraction Techniques on The Yield of Menthol: Review <p><em>One</em><em> of the ingredients in essential oils is menthol. Menthol is a compound in the form of crystals that has a mint-like aroma, providing a refreshing cool sensation. Extraction of plants to produce menthol can be done using hydrodistillation, steam distillation and microwave extraction methods. The difference in extraction methods will also determine the menthol that will be produced. This review contains the differences in extraction methods for plants that produce the highest yield of menthol in quantity. The design method used in this review is a systematic review, where the data obtained is a collection of several related studies. From the search results, the hydrodistillation method produced an average yield of menthol from the 5 sources of 58.09%, the steam distillation extraction method was 54.7%, and the microwave extraction was 28%. So the hydrodistillation method produces the largest yield of menthol in quantity compared to the steam distillation and microwave extraction methods.</em></p> Rima Nurlita, Amallia Fitri Dewi Mutya, Uswatun Hasanah Copyright (c) 2024 Rima Nurlita, Amallia Fitri Dewi Mutya, Uswatun Hasanah Wed, 22 May 2024 00:00:00 +0700