Effect of Simplicia Storage Temperature on the Curcumin Concentration of Temugiring (Curcuma heyneana Val.) Rhizome Simplicia

Authors

  • Anisa Lailatusy Syarifah AKFAR PIM
  • Rurini Retnowati Jurusan Kimia, FMIPA, Universitas Brawijaya, Malang, Indonesia
  • Christina Melani Brawijayanti Muda Makin Akademi Farmasi Putra Indonesia Malang

DOI:

https://doi.org/10.54445/pharmademica.v3i1.34

Abstract View:

321

PDF downloads:

326

Keywords:

Curcuma heyneana Val., curcumin, simplicia storage temperature

Abstract

The storage temperature of temugiring (Curcuma heyneana Val.) rhizome simplicia affects the curcumin active compound concentration in simplicia. This research aims to determine the effect of simplicia storage temperature on the curcumin compound concentration in temugiring rhizome simplicia. This is experimental research by various storage temperature of simplicia at 4, 15, 28, 37, and 40 0C for a month. Simplicia extraction was conducted by maceration method using ethanol 95% as a solvent with the ratio of simplicia powder and the solvent of 1:8. Determination of curcumin concentration was conducted by the UV-Vis spectrophotometry method at a wavelength of 420 nm. Data analysis was conducted by the one-way anova testing. Findings show that the highest to lowest curcumin concentration are at 280C of 51.360 ± 5.298 ppm, at 40C of 50.046 ± 5.177 ppm, at 150C of 42.000 ± 2.745 ppm, at 370C of 28.885 ± 4.155 ppm, and at 400C of 26.314 ± 4.843 ppm. In conclusion, the storage temperature affects the curcumin concentration of temugiring rhizome simplicia.

Temperatur penyimpanan simplisia rimpang temugiring (Curcuma heyneana Val.) mempengaruhi kandungan senyawa aktif kurkumin pada simplisia. Penelitian ini bertujuan untuk mengetahui pengaruh temperatur penyimpanan simplisia terhadap kadar senyawa kurkumin pada simplisia rimpang temugiring. Metode penelitian meliputi penyimpanan simplisia rimpang temugiring pada temperatur dingin (40C), sejuk (150C), ruangan (280C), panas (370C), dan sangat panas (400C) selama satu bulan. Ekstraksi simplisia dilakukan dengan metode maserasi menggunakan pelarut etanol 95% dengan perbandingan serbuk simplisia dan pelarut adalah 1:8. Penentuan kadar kurkumin dilakukan dengan metode spektrofotometri UV-Vis pada panjang gelombang 420 nm. Hasil penelitian menunjukkan kadar kurkumin tinggi pada temperatur penyimpanan ruangan (280C) sebesar 51,360 ± 5,298 ppm, dingin (40C) sebesar 50,046 ± 5,177 ppm, dan sejuk (150C) sebesar 42,000 ± 2,745 ppm. Kadar kurkumin rendah pada temperatur penyimpanan panas (370C) sebesar 28,856 ± 4,155 ppm, dan sangat panas (400C) sebesar 26,314 ± 4,843 ppm. Hal ini menunjukkan bahwa temperatur penyimpanan berpengaruh terhadap kadar kurkumin simplisia rimpang temugiring.

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References

Andini, A., Sari, M. I. ., Raharjo, S. J. ., & Anneke, A., 2023. Analysis and identification of flavonoid compounds in kepok banana corm extract (musa paradisiaca L). Jurnal Matematika Dan Ilmu Pengetahuan Alam LLDikti Wilayah 1 (JUMPA), 3(2), 65–71. https://doi.org/10.54076/jumpa.v3i2.300

Aggaarwal, B. S., 2006. Curcumin : The Indian Solid Gold, J. Sciences.vacte.5(1), 332.

Badan Pengawas Obat dan Makanan, 2005. Kriteria dan Tata Laksana Pendaftaran Obat Tradisional, Obat herbal Terstandar dan Fitofarmaka, Jakarta, Badan Pengawas Obat dan Makanan Republik Indonesia.

Departemen Kesehatan Republik Indonesia, 1985. Cara Pembuatan Simplisia, Jakarta, Departemen Kesehatan Republik Indonesia.

Fauzi, F., 2011. Uji Efek Proteksi Fraksi Etil Asetat Ekstrak Metanol Rimpang Temu Giring (Curcuma heyneana Val.) Terhadap Peningkatan Kadar Kolesterol Darah Tikus Jantan Galur Wistar Yang Diberi Diet Kolesterol Tinggi, Yogyakarta, Fakultas Farmasi Universitas Ahmad Dahlan.

Jayandran, M. H., 2015. Synthesis Characterization and Comparative Studies of Turmerice Oleoresin Derived from Selected Turmeric Plants. Asian Journal of Pharmaceutical Science & Technology, 5, 18-21.

Kusumaningrum, H. P., 2015. Kualitas Simplicia Tanaman Biofarmaka Curcuma domestica Setelah Proses Pemanasan Pada Suhu Dan Waktu Bervariasi, BIOMA, 27-33.

Maulida, A. N., 2015. Uji Efektivitas Krim Ekstrak Temu Giring (Curcuna heyneana Val.) sebagai Tabir Surya Secara In Vitro, Semarang, Universitas Negeri Semarang.

Rahayuda, I. G., 2016. Identifikasi Jenis Obat Berdasarkan Gambar Logo Pada Kemasan Menggunakan Metode Naive Bayes, Jurnal Sisfo, hal 17 - 32.

Suresh D, Manjunatha H and Srinivasan K, 2007, Effect of Heat Processing of Spices on The Concentrations of Their Bioactive Principles : Turmeric (Curcuma longa), red pepper (Capsicum annum) and black pepper (Piper nigrum), J. Food Compos Anal., 20, 346-351.

Syarifah, Anisa Lailatusy, Rurini Retnowati, Hermin Sulistyarti, 2019. Characterization of the Curcuminoids Fingerprint Profile in Curcuma and Zingiber Genera by TLC – Digital Image Analysis, J. Pure App. Chem. Res, 8 (2), 147-161

DOI: 10.21776/ub.jpacr.2019.002.001.462

Prasetyowati, R.D. and Anisa Lailatusy Syarifah, 2021, Pengaruh Temperatur Pengeringan Terhadap Kadar Kurkumin Ekstrak Rimpang Bangle (Zingiber Purpureum Roxb.), Akademi Farmasi Putra Indonesia Malang, 1-8. http://repository.poltekkespim.ac.id/id/eprint/598/

Wang YJ, Pan MH, Cheng AL, Lin LI, Ho YS, Hsieh CY and Lin JK, 1997. Stability of curcumin in buffer solutions and characterization of its degradation products, J. Pharm. Biomed. Anal., 15(12) : 1867-1876.

Widjaja, M., 2011. Validasi Metode Penetapan Kadar Kurkumin Dalam Sediaan Cair OHT Kiranti Secara Kromatografi Cair Kinerja Tinggi Fase Terbaik. Yogyakarta, Universitas Sanata Dharma.

Published

23-08-2023

How to Cite

Syarifah, A. L. ., Retnowati, R. ., & Makin, C. M. B. M. . (2023). Effect of Simplicia Storage Temperature on the Curcumin Concentration of Temugiring (Curcuma heyneana Val.) Rhizome Simplicia. PHARMADEMICA : Jurnal Kefarmasian Dan Gizi, 3(1), 1–10. https://doi.org/10.54445/pharmademica.v3i1.34