Optimization of PVA and HPMC in Peel-off Gel Face Mask Containing Beluntas Leaf Extract (Pluchea indica L.) Using the Simplex Lattice Design Method

Authors

  • Diny Puspitasari Poltekkes Wira Husada Nusantara Malang
  • Devina Wahyu Astaning Cristy Poltekkes Wira Husada Nusantara Malang
  • Fina Arista Langu Poltekkes Wira Husada Nusantara Malang

DOI:

https://doi.org/10.54445/pharmademica.v5i2.158

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6

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3

Keywords:

Peel-off gel mask, Pluchea indica, Polyvinyl alcohol, Hydroxypropyl methylcellulose, Simplex Lattice Design, Formula optimization

Abstract

Peel-off gel masks are widely used cosmetic skincare preparations due to their practicality, ease of removal, and non-comedogenic properties. Beluntas (Pluchea indica L.) leaf contains various bioactive compounds, particularly flavonoids, which possess antibacterial activity. This study aimed to obtain the optimum formulation of a peel-off face mask containing Beluntas leaf extract, with variations in Polivinyl alcohol (PVA) as a film-forming agent, and hydroxypropyl methylcellulose (HPMC) as a gelling agent.This experimental study employed the Simplex Lattice Design (SLD), an optimization method. Five formulations were prepared with PVA content ranging from 10-16% and HPMC concentrations from 2-4%. Each formulation was evaluated for organoleptic properties, homogeneity, pH, spreadability, drying time, adhesion, and viscosity, and the data were analyzed using Design Expert Version 13. The optimum peel-off gel mask formulation containing Beluntas leaf extract was obtained at PVA 12.92% and HPMC 3.07% with predicted spreading power 5.198, adhesion 52.910, viscosity 586.357, pH 4.626, drying time 23.502 with desirability 0.812.

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Published

30-03-2026

How to Cite

Puspitasari, D., Cristy, D. W. A. ., & Langu, F. A. . (2026). Optimization of PVA and HPMC in Peel-off Gel Face Mask Containing Beluntas Leaf Extract (Pluchea indica L.) Using the Simplex Lattice Design Method. PHARMADEMICA : Jurnal Kefarmasian Dan Gizi, 5(2), 208–220. https://doi.org/10.54445/pharmademica.v5i2.158

Issue

Vol. 5 No. 2 (2026): Oktober - Maret

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Articles

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Copyright (c) 2026 Diny Puspitasari, Devina Wahyu Astaning Cristy, Fina Arista Langu

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