Formulation and Evaluation of Belt Leaf Extract Cream Preparation with Varied Concentrations Of 96% Ethanol as Anti-Septic

Authors

  • Hilfa Qurrotul Aini Universitas Muhammadiyah Gresik
  • Pemta Tiadeka Universitas Muhammadiyah Gresik
  • Janatun Naimah Universitas Muhammadiyah Gresik

DOI:

https://doi.org/10.54445/pharmademica.v3i2.46

Abstract View:

47

PDF downloads:

40

Keywords:

Cream, Betel leaves, flavonoids, concentration variations

Abstract

The betel leaf plant (Piperis betle Linn) is a plant that is very easy to find in the surrounding environment. One of the benefits of the betel leaf plant is for treatment as an antiseptic because it contains flavonoid compounds. In order to make it easier for users to use betel leaves (Piperis betle Linn) as an antiseptic, the leaves are extracted with 96% ethanol and then formulated in cream form. This research aims to determine the results of concentration variations on the antiseptic activity of 96% ethanol extract cream from betel leaves on wound healing. Betel leaves (Piperis betle Linn) were extracted using the maceration method using 96% ethanol. Then the extract is made into a cream mass with varying concentrations of the active substance of 4%, 8% and 12%. The results of research on the formulation and evaluation of betel leaf extract cream can be concluded that betel leaves can be formulated as an antiseptic. The results of the physical evaluation show that the betel leaf extract cream has the best preparation in formula II with a concentration of 4% because the cream is included in the test range).

Downloads

Download data is not yet available.

References

Nuralifah, N., Fery Indradewi Armadany, P. Parawansah, and Aulif Pratiwi. 2019. “Uji Aktivitas Antibakteri Sediaan Krim Anti Jerawat Ekstrak Etanol Terpurifikasi Daun Sirih (Piper Betle L.) Dengan Basis Vanishing Cream Terhadap Propionibacterium Acne.” Pharmauho: Jurnal Farmasi, Sains, Dan Kesehatan 4(2). doi: 10.33772/pharmauho.v4i2.6261.

Widiarto, Mahendra, Muhammad Abdurrahman Janiarta, Putri Komala Intan, and Titi Laily Hajiriah. 2018. “ANALISIS KANDUNGAN ANTISEPTIK GETAH TUMBUHAN PATIKAN KEBO (Euphorbia Hirta) SEBAGAI DASAR PEMBUATAN BROSUR PENANGANAN LUKA RINGAN PADA MASYARAKAT.” Bioscientist : Jurnal Ilmiah Biologi 6(1):16. doi: 10.33394/bjib.v6i1.939.

Mahendra W, Abdurrahman, J.M., Kumala I.P. dan Laili. H. T. 2018. Analisis kandungan antiseptik getah tumbuhan patikan kebo (Euphorbia hirta) sebagai dasar pembuatan brosur penanganan luka ringan pada masyarakat. Jurnal Ilmiah Biologi. Vol.6, No.2, Hlm: 2338-5006. https://e-journal.undikma.ac.id/index.php/bioscientist/article/view/939

Asri, Muhammad. 2017, "Pengaruh Efek Ekstrak Etanol Daun Sirih (Piper Betle Linn) Sebagai Antioksidan Terhadap Luka Bakar pada Kulit Punggung Kelinci (Orictolagus Cuniculus)". As-Syifa. Vol 09 No.02. Hlm 182-187 https://www.academia.edu/download/92497612/pdf.pdf

Purwaningsih,Sri.Ela Sulamah, Tika A. Budiarti. 2014. Formulasi Skin Lotion Dengan Penambahan Karagenan dan Antioksidan Alami dari Rhizopora mucronata lamk. Jurnal Akuatika. Vol 5 No.1. Hlm 55-61 http://jurnal.unpad.ac.id/akuatika/article/view/3705

Endritayno, Nur Cholis dan Diah Nita Puspitasari. 2023. Formulasi Krim Ekstrak Daun Sirih Cina (Peperomia pellucida L.) Dengan Variasi Konsentrasi Trietanol dan Asam Stearat. Forte Jurnal. Vol 03 No. 01. Hlm 33-42 https://ojs.unhaj.ac.id/index.php/fj/article/view/416

Maya, Ira dan Mustakin. 2019. Review artikel: Formulasi dan Evaluasi Secara Fisiokimia Sediaan Krim Anti-aging. Farmaka. Vol 17 No,02. Hlm 296-305 https://journal.unpad.ac.id/farmaka/article/view/22115

Ulviani, Fina, Yusriadi dan Khildah Khaerati. 2016. Pengaruh Gel Ekstrak Daun Sirih Merah (Piper crocatum Ruiz dan pav ) Terhadap Penyembujan Luka Bakar Pada Kelinci (Orytolagus ciniculus). Galenika Journal Of Pharmacy.. Vol 02 No 02. Hlm 103-110. https://bestjournal.untad.ac.id/index.php/Galenika/article/view/5977

Bustanussalam, Devi Apriasi, Eka Suhardi dan Dadang Jaenudin. 2015. Efektivitas Antibakteri Eksyrak Daun Sirih (Piper Betle Linn) Terhadap Staphylococcus aureus ATCC 25923. Fitofarmaka. Vol 05 No.02. Hlm 58-64

Fathoni, Dhika Satriawan, Ilham Fadhilah dan Mujtahid Kaavessina. 2019. "Efektivitas Ekstrak Daun Sirih Sebagai Bahan Aktif Antibakteri Dalam Gel Handsaniizer Non-Alkohol". Equilibrium. Vol 03 No. 01. Hlm 10-14 https://jurnal.uns.ac.id/equilibrium/article/view/43215

Published

29-04-2024

How to Cite

Aini, H. Q., Tiadeka, P. ., & Naimah, J. . (2024). Formulation and Evaluation of Belt Leaf Extract Cream Preparation with Varied Concentrations Of 96% Ethanol as Anti-Septic. PHARMADEMICA : Jurnal Kefarmasian Dan Gizi, 3(2), 63–71. https://doi.org/10.54445/pharmademica.v3i2.46