Physical Qualities and Antifungal Activity of Cucumber (Cucumis sativus) Extract Shampoo against Candida albicans
DOI:
https://doi.org/10.54445/pharmademica.v4i2.58
Abstract View:
198
PDF downloads:
161
Keywords:
antifungal, Candida albicans, cucumber, dandruff, shampooAbstract
Dandruff can be caused by microorganisms such as fungi, one of which is Candida albicans. Candida albicans fungus can be inhibited with flavonoids, saponins, and alkaloids. One of the plants that contain this compound is cucumber (Cucumis sativus). Cucumbers are also able to stimulate hair growth and nourish hair loss. This research aims to determine the physical quality to determine quality and antifungal activity of cucumber fruit extract shampoo. The method used in this research was quantitative experimental with four formulas for varying the concentration of active substances from cucumber: F1 (0%), F2 (0.06%), F3 (0.08%), and F4 (0.1%). Cucumber extraction was done using the soxhletation method using 70% ethanol solvent. The organoleptic test results showed that F0, F1, F2, and F3 had a clear yellow color, a typical herbal odor, thick texture; and homogeneous. The pH of F0, F1, F2, and F3 respectively is 8.52; 8.76; 8.62 and 8.86. The viscosities of F0, F1, F2, and F3 are 1352 mPas, 1441 mPas, 1631 mPas, dan 1690 mPas, respectively. The height of the foam F0, F1, F2, and F3 respectively is 8.3 cm; 8.6cm; 8.6cm; and 8 cm. Antifungal activity has an inhibition zone of F0, F1, F2, and F3 respectively, namely 21.22 mm; 22.47mm; 22.82mm; 24.35mm. The results obtained show that the cucumber extract shampoo meets the physical qualities and has very strong antifungal activity.
Downloads
References
Agustin dan Shirly, 2019. 2019. “Uji Fitokimia Dan Aktivitas Antioksidan Ekstrak Mentimun (Cucumis Sativus).” Jurnal Lmiah Mahasiswa Pertanian Unsyiah 1(3):662–67.
Andiva, Hana Ayu, Makhabbah Jamilatun, and Pradea Indah Lukito. 2023. “Formulasi Dan Evaluasi Sabun Cair Kombinasi Ekstrak Kulit Nanas Madu (Ananas Comosus (L) Merr .) Dan Gel Lidah Buaya (Aloe Vera (L) Webb .).” Jurnal Jamu Kusuma 3(1):35–41.
Aryantini, Dyah, Lia Agustina, Ida Kristianingsih, Evi Kurniawati, and Ilham Khawarizmy. 2020. “Formulasi Dan Karakteristik Fisik Soothing Gel Kombinasi Lidah Buaya Dan Buah Naga.” Cendekia Journal of Pharmacy 4(1):1–9. doi: 10.31596/cjp.v4i1.51.
Badan Standarisasi Nasional. 1992. Shampoo. No. 06-2629-1992. Jakarta: Badan Standarisasi Nasional.
Bassy, La Lukman, Risman Tunny, and Wulandari Sri Sahari. 2023. “Uji Aktivitas Antibakteri Ekstrak Etanol Mentimun (Cucumis Sativus L) Asal Desa Waimital Terhadap Pertumbuhan Bakteri Propionibacterium Acnes Dengan Metode Difusi Sumuran.” Jurnal Ilmiah Ilmu 1(2):164–75.
Desriani, D., Nur Azizah, Ririn Wahyuni, and Andi Eka Purnama Putri. 2018. “Formulasi Hair Tonic Ekstrak Buah Mentimun (Cucumis Sativus) Sebagai Solusi Ketombe Dan Rambut Rontok Pada Wanita Berhijab.” Pharmauho: Jurnal Farmasi, Sains, Dan Kesehatan 4(1):39–41. doi: 10.33772/pharmauho.v4i1.4633.
Fauziah, Dewi Winni, and Galuh Karnia Yamaesa. 2019. “Formulasi Sampo Ekstrak Daun Mangga (Mangifera Indica L. ).” Jurnal Ilmiah Farmacy 6(1):5–10.
Febriani, D. A., A. Darmawati, and E. Fuskhah. 2021. “Pengaruh Dosis Kompos Ampas Teh Dan Pupuk Kandang Ayam Terhadap Pertumbuhan Dan Produksi Mentimun.” Cucumis Sativus L.). Jurnal Buana Sains 21(1):2527–5720.
Gebriella. 2021. “Pembuatan Sampo Anti Kutu Rambut Dari Ekstrak Daun Jeruk Purut (Citrus Hystrix DC).” Universitas Islam Negeri Alauddin Makassar.
Ginting, Ovalina Sylvia Br., Robiatun Rambe, Athaillah Athaillah, and Pinte Mahara HS. 2021. “Formulasi Sediaan Sampo Anti Ketombe Ekstrak Daun Binahong (Anredera Cordifilia (Tenore) Steen) Terhadap Aktivitas Jamur Candida Albicans Secara In Vitro.” Forte Journal 1(1):57–68. doi: 10.51771/fj.v1i1.40.
Gopalakrishnan, Subarayan Bothi, and Thangaraj Kalaiarasi. 2014. “Screening of Various Extracts of the Fruits of Cucumis Sativus Linn. for Antimicrobial Activity.” International Journal of Research and Development in Pharmacy and Life Sciences 3(5):1200–1205.
Hanni Endarini, Lully, Diah Titik Mutiarawati, and Alda Nugrahini. 2022. “Pertumbuhan Bakteri Bacillus Cereus Dan Salmonella Typhi Pada Ekstrak Mentimun (Cucumis Sativus).” Jurnal Penelitian Kesehatan Suara Forikes 13(17):663–66.
Hidayati, Rahmania, Yuli Nurullaili Efendi, Dyah Anggraeni, and Budhi Pratiwi. 2024. “Formulasi Sampo Ekstrak Daun Kesum (Polygonum Minus Huds) Dan Uji Efektivitas Antijamur Terhadap Candida Albicans.” AKFARINDO 9(1):16–24.
Iskandar, Benni, Leny Leny, and Akhmad Fajri Widodo. 2023. “Sediaan Sampo Dari Ekstrak Etanol Daun Sintrong (Crassocephalum Crepidioides): Formulasi, Karakterisasi Fisik Dan Uji Aktivitas Anti Jamur.” Majalah Farmasetika 8(5):459. doi: 10.24198/mfarmasetika.v8i5.47390.
Jamilatun, Makhabbah, and Aminah Aminah. 2017. “Isolasi Dan Identifikasi Fungi Patogen Di Kolam Renang Kota Tangerang.” Jurnal Ilmu Dan Teknologi Kesehatan 4(2). doi: 10.32668/jitek.v4i2.77.
Jamilatun, Makhabbah, Aminah Aminah, and Shufiyani Shufiyani. 2020. “Uji Daya Hambat Antibakteri Kapang Endofit Dari Tanaman Alang-Alang (Imperata Cylindrica (L.) BEAUV.) Terhadap Pertumbuhan Bakteri Staphylococcus Aureus Dan Escherichia Coli.” Jurnal Medikes (Media Informasi Kesehatan) 7(2). doi: 10.36743/medikes.v7i2.224.
Jamilatun, Makhabbah, Pradea Indah Lukito, and Melisa Angraini Saputri. 2023. “Physical Quality and Sun Protection Factor Value of The Sunscreen Lotion Extract of Carrot ( Daucus Carota L .).” 2(9):4258–62.
Jamilatun, Makhabbah, Melinda Dwi Pratiwi, and Susilo Yulianto. 2024. “Formulation and Evaluation of Face Mask Gel Peel Off Combination of Avocado Leaf Extract ( Perssea Americana Mill ) and Jicama ( Pachyrrhuzul Erosus L .).” 3(8):1739–48.
Jamilatun, Makhabbah, Harmayanti Aidha Rahmadianty, and Pradea Indah Lukito. 2023. “Quality Analysis of Cream Scrub Combination of Moringa ( Moringa Oleifera ) Leaf Extract and White Glutinous Rice ( Oryza Sativa Glutinosa ) Starch.” 1(03):302–11.
Karuna, Eric. 2022. “Penentuan Tingkat Kerontokan Rambut Kepala Pada Laki-Laki Dengan Menggunakan Metodefuzzy Inference System Sugeno.” Universitas Multidata Palembang.
Lukito, Pradea Indah, Makhabbah Jamilatun, and Innaya Rahma Salsabila. 2024. “Antibacterial Activity of Nginang Herb Extract Mouthwash Formulation Against The Streptococcus Mutans Bacteria.” International Journal of Science and Environment (IJSE) 4(2):47–51. doi: https://doi.org/10.51601/ijse.v4i2.97.
Mahulauw, Azril Hardiman, Djulfikri Mewar, Sri Wulandari Sahari, and Syamsuhidayat Hutapea. 2024. “Uji Aktivitas Antibakteri Ekstrak Etanol Daun Mentimun ( Cucumis Sativus L .) Asal Desa Waimital Terhadap Pertumbuhan Bakteri Propionibacterium Acnes Dengan Metode Difusi Sumuran STIKes Maluku Husada Sebutan Papinyo , Masyarakat Desa Waimital Biasanya Memanfaatkan Buah Mentimun Sebagai.” (1).
Maisarah, Mesy, Moralita Chatri, and Linda Advinda. 2023. “Karakteristik Dan Fungsi Senyawa Alkaloid Sebagai Antifungi Pada Tumbuhan.” Jurnal Serambi Biologi 8(2):231–36.
Malonda, Tasya C., Paulina V. Y. Yamlean, and Gayatri Citraningtyas. 2017. “Formulasi Sediaan Sampo Antiketombe Ekstrak Daun Pacar Air (Impatiens Balsamina L .) Dan Uji Aktivitasnya Terhadap Jamur Candida Albicans ATCC 10231 Secara In Vitro.” 6(4).
Mawaddah, N. 2021. Pembuatan Sampo Anti Kutu Rambut Dari Ekstrak Daun Jeruk Nipis.
Minarni, and Dewi Rosmalia. 2022. “Uji Daya Hambat Antibakteri Ekstrak Bonggol Nanas Terhadap Bakteri Streptococcus Mutans.” Jurnal Kesehatan 8(1):10–15. doi: https://doi.org/10.35730/jk.v13i1.707.
Nurhikma, Eny, Dewi Antasari, and Austin Selfyana tee. 2018. “Formulasi Sampo Antiketombe Dari Ekstrak Kubis Kombinasi Ekstrak Daun Pandan Wangi.” Jurnal Mandala Pharmacon Indonesia 4(1):61–67.
Nuzulandri, Julia. 2018. “Formulasi Dan Uji Efektivitas Pengawet Pada Tablet Tepung Belut (Monopterus Albus Zuiew).” Sekolah Tinggi Farmasi Indonesia Yayasan Petintis Padang 22–23.
Sitompul, Mardinda Bellia, Paulina V. Y. Yamlean, and Novel S. Kojong. 2016. “Formulasi Dan Uji Aktivitas Sediaan Sampo Antiketombe Ekstrak Etanol Daun Alamanda (Allamanda Cathartica L .) Terhadap Pertumbuhan Jamur Candida Albicans Secara In Vitro.” 5(3):122–30.
Surani, Fanni, and Norisca Aliza Aliza. 2017. “Evaluasi Berbagai Sediaan Shampo Herbal Antiketombe Dan Dantikutu.” Farmaka : Program Studi Sarjana Farmasi Fakultas Farmasi. Universitas Padjadjaran 15(2):218–32.
Suriaman, E., A. S. H. Permana, and Warman. 2016. “Aktivitas Antibakteri Ekstrak Etanol Buah Mentimun (Cucumis Sativus L.) Terhadap Salmonella Typhi Dan Bacillus Cereus Secara In Vitro.” Stigma Journal of Science 9(1):1–5.
Suryani, Ade Irma, and Eneng Ikrimah Rohwah. 2024. “Uji Aktivitas Sediaan Sampo Antiketombe Ekstrak Daun Ketepeng Cina (Cassia Alata L) Terhadap Jamur Pityrosporum Ovale.” Journal Syifa Sciences and Clinical Research 5(3):411–23. doi: 10.37311/jsscr.v5i3.24310.
Susila Ningsih, Idos, Moralita Chatri, and Linda Advinda. 2023. “Senyawa Aktif Flavonoid Yang Terdapat Pada Tumbuhan.” Serambi Biologi 8(2):126–32.
Tranggono, Retno Iswari, and Fatimah Latifah. 2014. “Buku Pegangan Ilmu Pengetahuan Kosmetologi.” Buku Pegangan Ilmu Pengetahuan Kosmetik.
Utami, Nurul, Army Auliah, and Iwan Dini. 2022. “Studi Kandungan Senyawa Metabolit Sekunder Beberapa Ekstrak Tai Anging (Usnea Sp.) Dan Uji Bioaktivitasnya Terhadap (Candida Albicans).” Chemica: Jurnal Ilmiah Kimia Dan Pendidikan Kimia 23(1):90. doi: 10.35580/chemica.v23i1.34077.
Vicky Wijoyo. 2016. “Optimasi Formula Sediaan Gel Hand Sanitizer Minyak Atsiri Jeruk Bergamot Dengan Gelling Agent Carbopol Dan Humektan Propilen Glikol.” Universitas Sanata Dharma.
Yulia, Resti, Moralita Chatri, Linda Advinda, and Dezi Handayani. 2023. “Senyawa Saponin Sebagai Antifungi Terhadap Patogen Tumbuhan.” Serambi Biologi 8(2):2023.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Makhabbah Jamilatun, Youstiana Dwi Rusita, Esti Perwita Sari
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
.png)
