TY - JOUR AU - Wardana, Fendi Yoga AU - Fadila, Nurul AU - Siwi, Mayang Aditya Ayuning PY - 2022/03/25 Y2 - 2024/03/29 TI - Identification of Salicylic Acid Content in Anti-Acne Cream Products at Tajinan Market Malang Regency JF - PHARMADEMICA : Jurnal Kefarmasian dan Gizi JA - PHARMADEMICA VL - 1 IS - 2 SE - Articles DO - 10.54445/pharmademica.v1i2.18 UR - https://jurnal.poltekkespim.ac.id/index.php/pharmademica/article/view/18 SP - 69-79 AB - <p><em>Anti-acne cream is a type of cosmetics that is often used for skin care. Salicylic acid is often used as the active substance in this anti-acne cream. According to the Indonesian National Food and Drug Agency in 2019 on cosmetics, salicylic acid is allowed in cosmetics if it is not more than 2%.</em> <em>In this study, 6 types of anti-acne cream, from Tajinan Market, Malang Regency, were tested with the aim of studying the content of salicylic acid in anti-acne cream products. The test was performed qualitatively using a colour test with FeCl<sub>3</sub> reagent (a positive reaction show a purple colour) and a thin layer chromatography (TLC) method using a solvent mixture of ethyl acetate;methanol;ammonia (8:1.90:0.10) as the mobile phase. Quantitative determination of the content was performed using UV-Vis spectrophotometry. The qualitative test with the colour test indicates that samples A and E are positive for containing salicylic acid. The results of the thin layer chromatography (TLC) test indicates that sample A is positive for containing salicylic acid with an Rf value of 0.66, which is the same as the comparison standard. The quantitative test with UV-Vis spectrophotometry indicates that the salicylic acid content in sample A is 2.516%, sample D is 1,400%, and sample E is 1.646%. In conclusion, only cream of sample A do not meet the requirements of the Indonesian National Food and Drug Agency because it has a salicylic acid content of more than 2%.</em></p> ER -